http://www.ureiko-chem.com/inh....ibitors-agonists/cel Small molecules Cell Cycle/DNA Damage Chemical Structure : Adavosertib CAS No.: 955365-80-7 聽 Adavosertib(AZD-1775;MK-1775) Catalog No.: URK-V1391聽聽Only Used For Lab. A potent and selective small-molecule inhibitor of Wee1 kinase with IC50 of 5.2 nM. 聽 Biological Activity A potent and selective small-molecule inhibitor of Wee1 kinase with IC50 of 5.2 nM; exhibits ATP-competitive and highly selective against other serine/threonine or tyrosine kinases; inhibits phosphorylation of CDC2 at Tyr15 in cells; potentiates tumor growth inhibition in vivo. Lung Cancer Phase
Like
Comment
Reward
Share
